Refine
Keywords
- Arzneimittel (1)
- Bewertung (1)
- Calibration (1)
- Diagnostik (1)
- Dispersion (stat) (1)
- Driving (veh) (1)
- Driving aptitude (1)
- Droge (1)
- Drugs (1)
- Drunkenness (1)
Institute
Chronic non-cancer pain (CNCP) is a major health problem. Patients are increasingly treated with chronic opioid therapy (COT). Several laboratory studies have demonstrated that long-term use of opioids does not generally impair driving related skills. But there is still a lack of studies investigating on-the-road driving performance in actual traffic. The present study assessed the impact of COT on road-tracking and car-following performance in CNCP patients. Twenty CNCP patients, long-term treated with stable doses of opioid analgesics, and 19 healthy controls conducted standardized on-the-road driving tests in normal traffic. Performance of controls with a blood alcohol concentration (BAC) of 0.5 g/L was used as a reference to define clinically relevant changes in driving performance. Standard Deviation of Lateral Position (SDLP), a measure of road-tracking control, was 2.57 cm greater in CNCP patients than in sober controls. This difference failed to reach statistical significance in a superiority test. Equivalence testing indicated that the 95% CI around the mean SDLP change was equivalent to the SDLP change seen in controls with a BAC of 0.5 g/L and did not include zero. When corrected for age differences between groups the 95% CI widened to include both the alcohol reference criterion and zero. No difference was found in car-following performance. Driving performance of CNCP patients did not significantly differ from that of controls due to large inter-individual variations. Hence in clinical practice determination of fitness to drive of CNCP patients who receive opioid treatments should be based on an individual assessment.
As bearing capacity measurements become more and more important, the necessity of assuring quality by establishing a QA system becomes more relevant. Within this context, the FGSV recommends the introduction of comparative measurements. Since 2015, two pilot events took place, with the main aim of introducing repetitive comparative measurements, in which all FWD operators shall participate. The results of the comparative measurements show that the basic principles behind comparative measurements (of the FWD), elaborated as a Europe-wide consensus and put into practice in the Netherlands and the United Kingdom, are valid, but still there is a variety of questions to be answered concerning certain details of the measuring system itself, e. g. measurement of the temperatures (air, pavement) and the impact of load introduction. All in all, the two pilot events in 2015 and 2016 proved that the comparability of the different FWD measuring devices is satisfactory.